n/a Document and Entity Information Statement [Table] Statement [Line Items] Statement [Line Items] Line items Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Entity Well-known Seasoned Issuer Entity Voluntary Filers Entity Current Reporting Status Entity Filer Category Entity Common Stock, Shares Outstanding Entity Public Float Document Fiscal Year Focus Document Fiscal Period Focus Balance Sheets Assets [Abstract] Assets Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents, end of period Cash and cash equivalents, beginning of period Cash and cash equivalents Restricted Cash and Cash Equivalents, Current Restricted cash Restricted cash, current Accounts Receivable, Net, Current Accounts receivable Other Receivables, Net, Current Other receivable Due from Affiliate, Current Due from former parent Inventory, Net Inventory Deferred Offering Costs Deferred offering costs Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Assets, Current Total current assets Property, Plant and Equipment, Net Land, property and equipment, net Property and equipment, net Goodwill Goodwill at end of the period Goodwill at beginning of the period Goodwill Goodwill on acquisition Intangible Assets, Net (Excluding Goodwill) Intangible assets, net Other Assets. Other assets Assets Segment assets Total assets Liabilities and Equity [Abstract] Liabilities, Convertible Preferred Stock and Stockholders' Equity (Deficit) Current liabilities: Accounts Payable, Current Accounts payable Represents the information pertains to carrying amount of consideration received or receivable as of the balance sheet date by virtue of collaboration agreements Deferred Collaboration revenue Current Deferred collaboration revenue Deferred Revenue, Current Deferred product revenue Deferred Rent Credit, Current Deferred rent Accrued Liabilities, Current Accrued expenses Total Warrants and Rights Outstanding Warrant liability Embedded Derivative, Fair Value of Embedded Derivative Liability Derivative liability Deferred Compensation Liability, Current Conversion option liability Convertible Notes Payable, Current Convertible notes payable Convertible notes payable - current Notes Payable, Current Notes payable Long-term Debt, Current Maturities Current portion of long-term debt Current portion of long-term debt Liabilities, Current Total current liabilities Long-term Debt, Excluding Current Maturities Long-term debt, net of discount Long-term debt, net of discount Convertible Notes Payable, Noncurrent Convertible notes payable Convertible notes payable - non-current Deferred Rent Credit, Noncurrent Deferred rent Liabilities Total liabilities Commitments and Contingencies. Commitments and Contingencies (See Note 7) Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity (Deficit): Preferred Stock, Value, Outstanding Preferred stock: $0.0001 par value, 10,000,000 shares authorized at December 31, 2017 and December 31, 2016; no shares issued and outstanding at December 31, 2017 and December 31, 2016. Common Stock, Value, Issued Common stock value Additional Paid in Capital, Common Stock Additional paid-in capital Retained Earnings (Accumulated Deficit) Accumulated deficit Stockholders' Equity Attributable to Parent Balance Balance Total stockholders' equity (deficit) Liabilities and Equity Total liabilities, convertible preferred stock and stockholders' equity (deficit) Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred stock, shares authorized Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Common stock par value (in dollars per share) Common Stock, Shares Authorized Common stock, shares authorized Number of shares authorizes to issue Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Outstanding Common stock, shares outstanding Statements of Operations and Comprehensive Loss Revenue, Net [Abstract] Revenue Sales Revenue, Goods, Net Product revenue Represents the amount pertains to recognition of collaboration revenue for the period Collaboration Revenue Net Collaboration revenue Revenues Revenue from external customers Total revenue Operating Expenses [Abstract] Operating Expenses CostOfRevenue Cost of product revenue Cost of revenue Research and Development Expense. Research and development expense Selling and Marketing Expense. Sales and marketing expense General and Administrative Expense. General and administrative expense Goodwill, Impairment Loss Impairment Impairment of goodwill Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) Impairment of indefinite-lived intangible assets Impairment Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Gross net operating loss Interest Expense. Interest expense Interest expense Other Nonoperating Income (Expense) Other income/(expense) Represents increase decrease in fair value of warrants. Increase Decrease In Fair Value Of Warrants Change in fair value of warrants Gains (Losses) on Extinguishment of Debt Loss on extinguishment of debt Loss on extinguishment of debt Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Net loss before income tax Net loss before income tax Income Tax Expense (Benefit) Income tax benefit Total provision for income taxes Net Income (Loss) Attributable to Parent Segment profit Net loss and comprehensive loss Earnings Per Share, Basic and Diluted Net loss per share, basic and diluted (in dollars per share) Net loss per share attributable to common shareholders, basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Weighted-average common shares outstanding, basic and diluted (in shares) Shares used to compute net loss per common share, basic and diluted (in shares) Statement of Changes in Common Stock and Stockholders' Equity (Deficit) Sale of Stock [Axis] Sale Of Stock Name Of Transaction [Domain] Sale of Stock [Domain] This member stands for secondary public offering February 2016. Secondary Public Offering February2016 [Member] Secondary Public Offering February 2016 Represents information pertaining to private investment in public entities June 2016. Private Investment In Public Entities June2016 [Member] Private Investment in Public Entities June 2016 Represents information pertaining to private investment in public entities. Private Investment In Public Entities [Member] Private Investment in Public Entities Information pertaining to private investment in public entities October 2016. Private Investment In Public Entities October2016 [Member] Private Investment in Public Entities October 2016 Information pertaining to private investment in public entities November 2016. Private Investment In Public Entities November2016 [Member] Private Investment in Public Entities November 2016 Represents information pertaining to private investment in public entities November 2017. Private Investment In Public Entities November2017 [Member] Private Investment In Public Entities November 2017 Represents information pertaining to private investment in public entities June 2017. Private Investment In Public Entities June2017 [Member] Private Investment in Public Entities June 2017 Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Common Stock [Member] Common Stock Additional Paid In Capital [Member] Additional Paid-in Capital Retained Earnings [Member] Deficit Accumulated During the Development Stage Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (decrease) in Stockholders' Equity (Deficit) Shares, Issued Balance (in shares) Balance (in shares) Issuance of common stock in a secondary public offering ,net of discounts and commissions Issuance Of Common Stock In A Secondary Public Offering Net Of Discounts And Commissions Issuance of common stock in a secondary public offering, net of discounts and commissions of $373,011 and offering costs of $496,887 February 2016 Issuance of common stock in a secondary public offering ,net of discounts and commissions in shares Issuance Of Common Stock In A Secondary Public Offering ,Net Of Discounts And Commissions In Shares Issuance of common stock in a secondary public offering ,net of discounts and commissions of $373,011 and offering costs of $496,887 February 2016 (in shares) Issuance of common stock in a private investment in public entities offering, net of offering costs Issuance Of Common Stock In A Private Investment In Public Entities Offering Net Of Offering Costs Issuance of common stock in a private investment in public entities offering, net of offering costs of $105,398, $72,710 and $6,000 Issuance of common stock in a private investment in public entities offering, net of offering costs in shares Issuance Of Common Stock In Private Investment In Public Entities Offering Net Of Offering Costs In Shares Issuance of common stock in a private investment in public entities offering, net of offering costs of $105,398, $72,710 and $6,000 (in shares) Issuance of common stock in a private investment in public entities offering Issuance Of Common Stock In A Private Investment In Public Entities Offering Issuance of common stock Issuance of common stock in a private investment in public entities offering in shares Issuance Of Common Stock In A Private Investment In Public Entities Offering In Shares Issuance of common stock (in shares) Equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering to a private investor. Stock Issued During Period, Value, New Issues, Private Investment Issuance of common stock and equity warrants in a private investment in public entities offering, net of warrant liability of $700,001 and net of offering costs of $96,833 November 2016 Number of new stock issued during the period to a private investor. Stock Issued During Period, Shares, New Issues, Private Investment Issuance of common stock and equity warrants in a private investment in public entities offering, net of warrant liability of $700,001 and net of offering costs of $96,833 November 2016 (in shares) Issuance of common stock through purchase agreement with private investors. Issuance of Common Stock through Stock Purchase Agreement with Private Investors Issuance of common stock through a stock purchase agreement with a private investor, net of offering costs of $44,738 November 2017 Issuance of common stock through purchase agreement with private investors in shares. Issuance of Common Stock through Stock Purchase Agreement with Private Investors, In Shares Issuance of common stock through a stock purchase agreement with a private investor, net of offering costs of $44,738 November 2017 (in shares) Stock Issued During Period, Value, Acquisitions Issuance of common stock in the merger Stock Issued During Period, Shares, Acquisitions Issuance of common stock in the merger (in shares) Aggregate value of common stock issued during the period in relation to follow-on offering registration statement. Issuance of Common Stock In Follow-on Offering Registration Statement, Value Issuance of common stock in a follow-on offering registration statement October 2017, net of commissions and offering costs of $763,502 The number of common stock issued during the period in relation to follow-on offering registration statement. Issuance of Common Stock In Follow-on Offering Registration Statement, Shares Issuance of common stock in a follow-on offering registration statement October 2017, net of commissions and offering costs of $763,502 (in shares) Conversion of non-voting common stock into common stock. Conversion of Non-voting Common Stock into Common Stock, Value Conversion of non-voting common stock to common stock Conversion of non-voting common stock into common stock in shares. Conversion of Non-voting Common Stock into Common Stock, Shares Conversion of non-voting common stock to common stock (in shares) Adjustments to Additional Paid in Capital, Warrant Issued Issuance of warrants in the merger Amount of increase in additional paid in capital (APIC) resulting from the issuance of stock options as part of acquisition consideration. Adjustments to Additional Paid in Capital, Stock Options Issued, Acquisitions Issuance of stock options in the merger Amount of increase in additional paid in capital (APIC) resulting from the issuance of restricted stock units or restricted stock awards, as part of acquisition consideration Adjustments to Additional Paid in Capital, Restricted Stock Unit or Restricted Stock Award, Acquisitions Issuance of RSUs in the merger Value of stock issued in exchange of warrants during the period. Stock Issued During Period, Value, Exchange of Warrants Issuance of common stock in exchange for warrants Number of shares of stock issued during the period in exchange of warrants. Stock Issued During Period, Shares, Exchange of Warrants Issuance of common stock in exchange for warrants (in shares) Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation Amount of warrants issued in conjunction with debt extinguishment. Warrants Issued in Conjunction with Debt Extinguishment Warrants, issued in conjunction with debt extinguishment Stock Issued During Period, Value, Restricted Stock Award, Gross Issuance of common stock in exchange for vested restricted stock units Stock Issued During Period, Shares, Restricted Stock Award, Gross Issuance of common stock in exchange for vested restricted stock units (in shares) Stock Issued During Period, Value, Conversion of Convertible Securities Issuance of common stock in exchange for redemption of convertible debt Stock Issued During Period, Shares, Conversion of Convertible Securities Issuance of common stock in exchange for redemption of convertible debt (in shares) Aggregate value of common stock issued during the period in exchange of services. Stock Issued During Period, Value, Exchange of Service Issuance of common stock in exchange for services Number of shares of stock issued during the period in exchange of service. Stock Issued During Period, Shares, Exchange of Service Issuance of common stock in exchange for services (in shares) Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss and comprehensive loss Net loss Net and comprehensive loss Member represents follow on offering registration. Follow On Offering Registration October2017 [Member] Follow-on Offering Registration October 2017 The member represents stock purchase agreement with private investor November 2017. Stock Purchase Agreement With Private Investor November2017 [Member] Stock Purchase Agreement with Private Investor November 2017 Stock Transactions, Parenthetical Disclosures [Abstract] Stock Transactions, Parenthetical Disclosures Investment Banking, Advisory, Brokerage, and Underwriting Fees and Commissions Underwriting discounts and commissions Other Financial Services Costs Offering expenses Offering costs Statements of Cash Flow Secondary public offering of common stock member Secondary Public Offering [Member] Secondary public offering Represents information pertaining to private investment in public entities December 2017. Private Investment In Public Entities December2017 [Member] Private Investment in Public Entities December 2017 Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Cash Flows from Operating Activities Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Depreciation, Depletion and Amortization Depreciation and amortization expense Depreciation and amortization Amount of interest paid on the conversion of debt to equity. Interest Paid On Conversion Of Debt To Equity Interest paid on the conversion of debt to equity Represents the fair value of common stock issued in relation to exchange of service rendered. Common Stock Issued in Exchange of Services Rendered Common stock issued in exchange for services rendered Impairment of Intangible Assets, Finite-lived Impairment of indefinite-lived intangible assets Deferred Income Tax Expense (Benefit) Deferred income tax benefit Total deferred Issuance of Stock and Warrants for Services or Claims Stock issued in Napo merger for services Fair value of shares issued to creditors (in shares) Amount of charge in relation to modification of warrants. Charge In Relation To Modification Of Warrants Charge in relation to modification of warrants The cash outflow for cost incurred directly with the issuance of warrants. Payments of Warrants Issuance Costs Issuance costs in connection with warrants issued in the November 2016 private investment in public entity Share-based Compensation Stock-based compensation Amortization of debt issuance costs and debt discount. Amortization of debt issuance costs and debt discount Fair Value Adjustment of Warrants Revaluation of warrant liability Change in fair value of warrants Amount of expense (income) related to adjustment to fair value of derivative liability. Fair Value Adjustment Of Derivative Liability Change in fair value of derivative liability Increase (Decrease) in Operating Capital [Abstract] Changes in assets and liabilities Increase (Decrease) in Accounts Receivable Accounts receivable - trade Increase (Decrease) in Other Receivables Other receivable Increase (Decrease) in Inventories Inventory Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase decrease during the reporting period specific incremental costs directly attributable to a proposed or actual offering of securities which are deferred at the end of the reporting period. Increase Decrease in Deferred Offering Costs Deferred offering costs Increase (Decrease) in Other Noncurrent Assets Other non-current assets Increase (Decrease) in Due to Related Parties, Current Due from former parent Represents the amount pertains to changes in deferred collaboration revenue for the period Increase Decrease In Deferred Collaboration Revenue Deferred collaboration revenue Increase (Decrease) in Deferred Revenue Deferred product revenue Increase decrease in deferred rent Increase decrease in deferred rent Deferred rent It represents the amount payable for license fee in operating activities. Increase Decrease In License Fee Payable License fee payable Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accrued Liabilities Accrued expenses Net Cash Provided by (Used in) Operating Activities Total cash used in operations Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Cash Flows from Investing Activities Payments to Acquire Property, Plant, and Equipment Purchase of equipment Payments to Acquire Businesses, Net of Cash Acquired Cash paid in Napo merger, net of cash acquired Increase (Decrease) in Restricted Cash Change in restricted cash Net Cash Provided by (Used in) Investing Activities Total cash (used in)/ provided by investing activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Cash Flows from Financing Activities Repayments of Long-term Debt Repayment of long-term debt Proceeds from Convertible Debt Proceeds from issuance of convertible debt Proceeds from Notes Payable Proceeds from issuance of notes payable The cash inflow associated with the amount received from a secondary offering of stock. Proceeds From Issuance Secondary Offering Proceeds from issuance of common stock in follow-on secondary public offering, net of commissions, discounts Payments of Stock Issuance Costs Deferred offering costs The cash inflow from issuance of common stock in a private investment in public entities offering. Proceeds From Issuance Of Common Stock In A Private Investment In Public Entities Offering Issuance of common stock in a private investment in public entities offering Proceeds from Issuance of Private Placement Proceeds from issuance of common stock in a private investment in public entities The total of the cash outflow during the period which has been paid to third parties in connection with issuance of common stock under private placement. Payment of Private Placement Issuance Cost, Common Stock Issuance costs associated with the proceeds from the issuance of common stock in a private investment in public entities The cash inflow from issuance of common stock through stock purchase agreement. Proceeds from Issuance of Common Stock through Stock Purchase Agreement Issuance of common stock through a stock purchase agreement with a private investor November 2017 The cash outflow for payment of common stock issuance costs through stock purchase agreement. Proceeds from Cost Associated With Issuance of Common Stock through Stock Purchase Agreement Issuance costs associated with the issuance of common stock through a stock purchase agreement - November 2017 The amount represents payment for issuance of common stock follow-on offering registration. Payment For Issuance Of Common Stock Follow-on Offering Registration Issuance of common stock in a follow-on offering registration statement October 2017 The amount represents payment for issuance cost associated with common stock in follow-on offering. Payment for Issuance Cost Associated With Common Stock In Follow-on Offering Issuance costs associated with the issuance of common stock in a follow-on offering registration statement October 2017 The cash inflow from issuance of common stock in relation to acquire businesses. Proceeds from Issuance of Common Stock, Acquire Businesses Proceeds from issuance of common stock in the Napo merger The cash inflow from issuance of common stock through exercise of common stock warrants. Proceeds from Issuance of Common Stock, Exercise of Common Stock Warrants Proceeds from the issuance of common stock through the exercise of common stock warrants Net Cash Provided by (Used in) Financing Activities Total Cash Provided by Financing Activities Cash and Cash Equivalents, Period Increase (Decrease) Net decrease in cash and cash equivalents